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4 ACETAMIDO TEMPO Powder

4 ACETAMIDO TEMPO Powder

Appearance: Orange red crystal powder
Specification: Min 98%
CAS: 14691-89-5
Molecular Formula: C11H21N2O2*
Molecular Weight: 213.3
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: COA,ISO,GMP, HACCP,SGS
Service: OEM Service(Private Package)

Giơi thiệu sản phẩm

 

4-ACETAMIDO-TEMPO Description
4 ACETAMIDO TEMPO powder is an organic compound; its chemical name is 4-Acetamido-2,2,6,6-tetramethylpiperidine-1-oxyl or AT-TEMPO for short. AT-TEMPO is mainly used to catalyze oxidation reactions. AT-TEMPO can be used as an oxidant or an auxiliary catalyst agent in such responses. When used as an oxidizing agent, it can be reduced to a free radical form, which can oxidize other groups. In other cases, AT-TEMPO can also be used as an auxiliary catalyst agent to promote the oxidation reaction. In addition to its application as an oxidizing agent and catalyst, AT-TEMPO has been widely used in materials science mainly because of its strong oxidizing effect. AT-TEMPO can also play a role in the biomedical field, where the most common application is quantifying lipid peroxide levels using the AT-TEMPO oxidant.
In addition, AT-TEMPO has also been used to improve recovery from trauma after cardiac surgery and reduce levels of oxidative stress that can harm the body. In particular, it has emerged as an essential tool in the total synthesis of methylenes, where its redox properties can facilitate alkylation and aldehyde reactions. In addition, AT-TEMPO can also be used to catalyze the oxidation of sulfur compounds.
It is a free radical with strong redox effects. It has broad applications in many fields, including catalytic oxidation reactions, materials science, biomedicine, and organic synthesis. Due to its strong redox properties, it has broad application potential in these fields. Xi'an Sonwu is an API 4 ACETAMIDO TEMPO manufacturer. If you need 4 ACETAMIDO TEMPO, you can contact Xi'an Sonwu online.

4-ACETAMIDO-TEMPO structure

 

Certificate Of Analysis

ANALYSIS

SPECIFICATION

RUSULT

Purity

≥ 98%

98.31%

Apperance

Orange red crystal powder

Conform

Identification

Positive reaction

Conform

Heavy Metal

≤ 100ppm

Conform

Water

≤ 5%

1.08%

Particle size

98% pass 80 mesh

Conform

Solubility

Soluble in ethanol, acetone, acetonitrile, methylene chloride. Insoluble in hexane, ether.

Conform

Melting point

143-145 °C (lit.)143-146 °C

144 °C

Boiling point

353.29°C (rough estimate)

Conform

Total plate count

1000cfu/g

Conform

Mold

100cfu/g

Conform

E.Coli

Negative

Negative

Salmonella

Negative

Negative

 

Where To Buy 4-ACETAMIDO-TEMPO
Xi'an Sonwu Biotech Co. ltd. is a manufacturer and distributor with over ten years of experience. It has extensive and stable cooperation with countries worldwide in the Americas, Asia, Europe, and Oceania. Xi'an Sonwu has always insisted on product quality first. Serving every customer well and satisfying every customer is Xi'an Sonwu's pursuit. Xi'an Sonwu strictly controls every step, from the selection of raw materials, and pursues high-quality products from all aspects, such as material selection, manufacturing, sample testing, and personnel professionalism. In addition, Xi'an Sonwu strives to do an excellent job in every detail to minimize the cost and help customers get cost-effective products. Based on these services, customers have given good feedback on the product. So if you need API 4 ACETAMIDO TEMPO, please contact Xi'an Sonwu.
Xi'an Sonwu ensures product quality so that the sample can be supplied. Here is the quantity.

4-ACETAMIDO-TEMPO Form

Sample Amount

MOQ

Powder

100g

100g

 

Customers' Good Comment

Xian Sonwu1

 

Mechanism Of Action Of 4-ACETAMIDO-TEMPO
4-ACETAMIDO-TEMPO is a free radical scavenger mainly used to scavenge oxygen and nitrogen free radicals. Its action is by reacting with free radicals, thereby inhibiting the oxidative damage and inflammation caused by them. Its targets are oxygen free radicals (O2•-) and hydroxyl radicals (HO•), which can protect cells, tissues, and organs from oxidative damage by capturing these free radicals. Its targets are mainly related to cell signaling pathways and molecular mechanisms, such as the NF-κB signaling pathway, mitochondrial function, protein ubiquitination, etc. In addition, it also has anti-inflammatory effects, can inhibit the activation of inflammatory cells, reduce inflammatory reactions and necrosis factor production, etc. It is also widely used to reduce DNA oxidative damage, protect cell membranes and neurons, etc.
Regarding biochemistry, the principle of AT-TEMPO is to capture oxygen free radicals and hydroxyl free radicals for redox reactions and convert these free radicals into stable products without oxidation ability, thereby inhibiting the damage of oxygen free radicals to organisms. In addition, API 4 acetamido tempo can also have antioxidant and anti-inflammatory effects through mechanisms such as improving mitochondrial function and reducing oxidative stress and apoptosis.

scavenge oxygen and nitrogen free radicals

 

4-ACETAMIDO-TEMPO Effect
1. Protect cells from oxidative damage
AT-TEMPO has a strong inhibitory effect on intracellular free radicals and can protect cells from oxidative damage. It protects cells from oxidative damage by trapping oxygen free radicals and other reactive oxidants, thereby reducing the oxidation of DNA, lipids, and proteins. In addition, 4-Acetamido-TEMPO can also enhance the antioxidant defense ability of cells by regulating specific signaling pathways. For example, 4-Acetamido-TEMPO can promote the activation of NF-E2 corresponding factor 2, and increase the expression of superoxide dismutase, glutathione peroxidase, NADH, quinoline oxidase 1, and other antioxidant enzymes in cells, thereby Enhance the antioxidant capacity of cells.
The pharmacological properties of 4-Acetamido-TEMPO also include its structural protection. Studies have shown that 4-Acetamido-TEMPO can protect cells by changing the lipid composition of cell membranes. The cell membrane is the boundary and isolation of various substances and components in the cell and is also the basis of many important receptors and channels. Oxidative damage will damage the integrity and stability of the cell membrane, so 4-Acetamido-TEMPO can protect cells by enhancing the strength of the cell membrane, thereby reducing the damage to cells caused by oxidative stress.

4-ACETAMIDO-TEMPO Effect1

 

2. Anti-inflammatory effect
4-ACETAMIDO-TEMPO can inhibit the inflammatory response, relieving pain, swelling, and other symptoms. First, AT-TEMPO can inhibit the release of cytokines, which are vital mediators leading to inflammatory responses. By inhibiting the release of cytokines, it reduces inflammation and tissue damage. Second, it neutralizes free radicals often produced during inflammatory reactions. Free radicals can damage cell membranes and DNA and induce inflammation. By neutralizing free radicals, 4-ACETAMIDO-TEMPO reduces inflammation and lessens tissue damage.
The anti-inflammatory effect of AT-TEMPO has been widely studied, and it has shown promising efficacy in animal experiments, especially in the control of neurodegenerative and cardiovascular diseases. This anti-inflammatory effect is critical to stabilization and recovery.

 

3. Antithrombotic effect
4 ACETAMIDO TEMPO powder can inhibit the aggregation of platelets, thereby reducing the formation of a thrombus. It has a perfect impact on preventing cardiovascular and cerebrovascular diseases. It has been shown to have significant antithrombotic and antiplatelet aggregation activities. Blood cells and protein clots combine to form a thrombus. It can cause substantial harm to the human body, such as myocardial infarction, stroke, and other diseases. The antithrombotic component of 4-AT lends it the potential to prevent these diseases.
Studies have shown that 4-AT can prevent thrombosis through multiple mechanisms. First, it reduces oxidative stress by scavenging free radicals, thereby preventing blood vessel damage. 4-AT can inhibit the activation and aggregation of platelets. Platelets are cells in the blood that stop bleeding. However, when platelets are overactivated, they can clump together to form blood clots. Studies have shown that 4-AT can reduce platelet aggregation and the level of thromboxane in platelets. Thromboxane is a platelet activator that can lead to platelet aggregation and thrombus formation. By inhibiting this process, 4-AT prevents the formation of blood clots.

4-ACETAMIDO-TEMPO Effect2

 

4. Improve immunity
4-ACETAMIDO-TEMPO can enhance human immunity and improve body resistance, thereby preventing the occurrence of diseases. The molecular structure of AC-TEMPO contains a chemical bond that can interact with free radicals and prevent them from causing damage to cells and tissues. AC-TEMPO is widely used in biomedical research, and multiple studies have shown that this compound can enhance the body's immunity, thereby reducing the incidence of diseases. When the human immune system is infected or attacked, it releases free radicals, which will cause damage to the health of the body and accelerate cell aging and tissue damage. And AC-TEMPO has a particular ability to scavenge these free radicals, which can alleviate the damage caused by free radicals.

 

Factory
1. Xi'an Sonwu Biotech Co., Ltd has its factory to produce, manufacture and store the products, so have adequate Stock. Xi'an Sonwu has a well-ordered, clean, and tidy production department. Under Xi'an Sonwu, researchers can continuously develop high-quality new products.
2. Xi'an Sonwu has strict requirements on personnel allocation from production and testing to sales. To ensure that each product is escorted, rigorous data support and after-sales service are provided.

factory 1

factory 2

 

Certificate

Xian Sonwu4

 

Packing

Xian Sonwu5

 

Logistics

Xian Sonwu2

Besides guaranteeing the product, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

logistics

 

FAQ
Commonly used as a chemical reagent, not suitable for internal human use. Therefore, research data on possible side effects of its use are limited.
However, some studies have shown that this compound may have adverse effects on human health at high concentrations, such as:
Skin irritation
Effects on breathing, vision, central nervous system, etc.
AT-TEMPO may cause an allergic reaction in some people.
Therefore, before using 4-ACETAMIDO-TEMPO, the relevant information should be read carefully, and appropriate safety measures should be taken.


If you want to get pure 4 ACETAMIDO TEMPO, you can contact Xi'an Sonwu. Click the email then you get high-quality 4 ACETAMIDO TEMPO powder.
Email: sales@sonwu.com

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